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49ers vs. Chargers Preview

NFL Week 15, 2026 season. Thursday, Dec 17, 2026, 7:15 PM CT. SoFi Stadium.

49ers
6-1 #1 in Buck's power rankings
at
Chargers
0-6 #32 in Buck's power rankings

The Sim's pick: sealed

The Sim has called this game. Its pick, win chance, and projected score unlock at kickoff, Thursday, 7:15 PM CT. Make yours first.

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The Sim's take

The 49ers come in 6-1, and Buck has them 1st. The Chargers come in 0-6, and Buck has them 32nd.

49ers: last 5 games

Chargers: last 5 games

Last meetings: 49ers vs. Chargers

  • 2022, Week 10 LAC 16 at SF 22 49ers won
  • 2018, Week 4 SF 27 at LAC 29 Chargers won
  • 2014, Week 16 LAC 38 at SF 35 (OT) Chargers won
  • 2010, Week 15 SF 7 at LAC 34 Chargers won
  • 2006, Week 6 LAC 48 at SF 19 Chargers won

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Schedule and scores: nflverse. Picks: the Sim, Hizzle's own model. Power rankings: Buck Kincaid. Times are Central. Not affiliated with the NFL.