Colts vs. Titans
NFL Week 3, 2025 season. Sunday, Sep 21, 2025, 12:00 PM CT. Nissan Stadium. Referee: Scott Novak.
The Sim's pick: Indianapolis Colts
Sim right
62% Colts
Titans 38%
- Projected score
- IND 25, TEN 21
- Sim line
- IND -3.5
- Backtest
- made after kickoff
Beat the Sim: your pick
Picks for this game locked at kickoff. See the standings.
The Sim's take
The Sim made the Colts a slight favorite on the road: 62% to beat the Titans, with a projected score of 25-21 (IND by 3.5).
The Colts came in 2-0. The Titans came in 0-2.
Final: Colts 41, Titans 20. The Sim's pick was right.
Colts: last 5 games
Titans: last 5 games
Last meetings: Colts vs. Titans
- 2024, Week 16 TEN 30 at IND 38 Colts won
- 2024, Week 6 IND 20 at TEN 17 Colts won
- 2023, Week 13 IND 31 at TEN 28 (OT) Colts won
- 2023, Week 5 TEN 16 at IND 23 Colts won
- 2022, Week 7 IND 10 at TEN 19 Titans won
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More Week 3 games
All Week 3 picks- Dolphins vs. Bills recap
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- Raiders vs. Commanders recap
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Schedule and scores: nflverse. Picks: the Sim, Hizzle's own model. Power rankings: Buck Kincaid. Times are Central. Not affiliated with the NFL.