Cardinals vs. 49ers
NFL Week 3, 2026 season. Sunday, Sep 27, 2026, 3:05 PM CT. Levi's Stadium. Referee: Brad Allen.
The Sim's pick: San Francisco 49ers
Sim right- Projected score
- ARI 18, SF 28
- Sim line
- SF -9.5
- Backtest
- made after kickoff
Beat the Sim: your pick
Picks for this game locked at kickoff. See the standings.
Cardinals vs. 49ers box score
Official stats. Updated .
Arizona Cardinals
| Passing | C/Att | Yds | Avg | TD | Int |
|---|---|---|---|---|---|
| Jacoby Brissett | 38/52 | 280 | 5.4 | 2 | 0 |
| Rushing | Car | Yds | Avg | TD | |
| Jeremiyah Love | 21 | 90 | 4.3 | 0 | |
| Jacoby Brissett | 4 | 4 | 1.0 | 1 | |
| Tyler Allgeier | 2 | -1 | -0.5 | 0 | |
| Receiving | Rec | Tgt | Yds | TD | |
| Michael Wilson | 11 | 17 | 89 | 1 | |
| Trey McBride | 9 | 11 | 75 | 0 | |
| Marvin Harrison Jr. | 3 | 5 | 40 | 0 | |
| Kendrick Bourne | 2 | 3 | 22 | 0 | |
| Elijah Higgins | 3 | 3 | 20 | 0 | |
| Jeremiyah Love | 5 | 5 | 19 | 1 | |
| Tyler Allgeier | 4 | 4 | 10 | 0 | |
| Hunter Long | 1 | 1 | 5 | 0 | |
| Jalen Brooks | 0 | 1 | 0 | 0 | |
| Kicking | FG | 50+ | XP | Pts | |
| Chad Ryland | 3/3 | 0 | 3/3 | 12 |
San Francisco 49ers
| Passing | C/Att | Yds | Avg | TD | Int |
|---|---|---|---|---|---|
| Brock Purdy | 15/27 | 297 | 11.0 | 4 | 0 |
| Rushing | Car | Yds | Avg | TD | |
| Christian McCaffrey | 15 | 75 | 5.0 | 1 | |
| Brock Purdy | 2 | 34 | 17.0 | 0 | |
| Kaelon Black | 4 | 17 | 4.3 | 0 | |
| Deebo Samuel Sr. | 2 | 14 | 7.0 | 0 | |
| Receiving | Rec | Tgt | Yds | TD | |
| George Kittle | 6 | 7 | 82 | 2 | |
| Deebo Samuel Sr. | 0 | - | 80 | 1 | |
| Jordan Watkins | 2 | 2 | 60 | 0 | |
| Christian McCaffrey | 4 | 5 | 41 | 0 | |
| Mike Evans | 3 | 6 | 34 | 1 | |
| Kyle Juszczyk | 0 | 2 | 0 | 0 | |
| Luke Farrell | 0 | 1 | 0 | 0 | |
| Jacob Cowing | 0 | 2 | 0 | 0 | |
| Kaelon Black | 0 | 1 | 0 | 0 | |
| Kicking | FG | 50+ | XP | Pts | |
| Eddy Pineiro | 1/1 | 1 | 3/5 | 6 |
Players are the ones Hizzle prices for Cap Space: quarterbacks, running backs, receivers, tight ends, and kickers.
The Sim's take
The Sim made the 49ers a heavy favorite at home: 80% to beat the Cardinals, with a projected score of 28-18 (SF by 9.5).
The Cardinals came in 1-1. The 49ers came in 2-0.
Final: Cardinals 30, 49ers 36. The Sim's pick was right.
Cardinals: last 5 games
49ers: last 5 games
Last meetings: Cardinals vs. 49ers
- 2025, Week 11 SF 41 at ARI 22 49ers won
- 2025, Week 3 ARI 15 at SF 16 49ers won
- 2024, Week 18 SF 24 at ARI 47 Cardinals won
- 2024, Week 5 ARI 24 at SF 23 Cardinals won
- 2023, Week 15 SF 45 at ARI 29 49ers won
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Schedule and scores: nflverse. Picks: the Sim, Hizzle's own model. Power rankings: Buck Kincaid. Times are Central. Not affiliated with the NFL.