49ers vs. Rams
NFL Week 1, 2026 season. Thursday, Sep 10, 2026, 7:35 PM CT. Melbourne Cricket Ground, neutral site. Referee: Alex Kemp.
The Sim's pick: Los Angeles Rams
Sim wrong- Projected score
- SF 23, LA 25
- Sim line
- LA -2
- Backtest
- made after kickoff
Beat the Sim: your pick
Picks for this game locked at kickoff. See the standings.
49ers vs. Rams box score
Official stats. Updated .
San Francisco 49ers
| Passing | C/Att | Yds | Avg | TD | Int |
|---|---|---|---|---|---|
| Brock Purdy | 25/34 | 205 | 6.0 | 3 | 1 |
| Rushing | Car | Yds | Avg | TD | |
| Christian McCaffrey | 10 | 68 | 6.8 | 0 | |
| Kaelon Black | 14 | 65 | 4.6 | 0 | |
| Brock Purdy | 5 | 29 | 5.8 | 0 | |
| Deebo Samuel Sr. | 1 | 12 | 12.0 | 0 | |
| Receiving | Rec | Tgt | Yds | TD | |
| Demarcus Robinson | 2 | 3 | 50 | 1 | |
| Mike Evans | 6 | 7 | 49 | 1 | |
| Deebo Samuel Sr. | 6 | 7 | 48 | 1 | |
| Christian McCaffrey | 5 | 8 | 20 | 0 | |
| Luke Farrell | 2 | 2 | 19 | 0 | |
| George Kittle | 2 | 5 | 12 | 0 | |
| Kaelon Black | 1 | 1 | 5 | 0 | |
| Kicking | FG | 50+ | XP | Pts | |
| Eddy Pineiro | 2/3 | 1 | 3/3 | 9 |
Los Angeles Rams
| Passing | C/Att | Yds | Avg | TD | Int |
|---|---|---|---|---|---|
| Matthew Stafford | 15/25 | 155 | 6.2 | 0 | 1 |
| Stetson Bennett | 2/3 | 13 | 4.3 | 0 | 0 |
| Rushing | Car | Yds | Avg | TD | |
| Blake Corum | 10 | 54 | 5.4 | 0 | |
| Kyren Williams | 11 | 41 | 3.7 | 1 | |
| Ronnie Rivers | 5 | 19 | 3.8 | 0 | |
| Stetson Bennett | 1 | 9 | 9.0 | 0 | |
| Matthew Stafford | 2 | -1 | -0.5 | 0 | |
| Receiving | Rec | Tgt | Yds | TD | |
| Puka Nacua | 5 | 9 | 74 | 0 | |
| Davante Adams | 3 | 6 | 26 | 0 | |
| Kyren Williams | 3 | 3 | 24 | 0 | |
| Davis Allen | 1 | 1 | 13 | 0 | |
| Tyler Higbee | 2 | 2 | 12 | 0 | |
| Jordan Whittington | 1 | 1 | 8 | 0 | |
| Colby Parkinson | 1 | 2 | 6 | 0 | |
| Ronnie Rivers | 1 | 1 | 5 | 0 | |
| Konata Mumpfield | 0 | 1 | 0 | 0 | |
| Terrance Ferguson | 0 | 1 | 0 | 0 | |
| Kicking | FG | 50+ | XP | Pts | |
| Harrison Mevis | 0/0 | 0 | 1/1 | 1 |
Players are the ones Hizzle prices for Cap Space: quarterbacks, running backs, receivers, tight ends, and kickers.
The Sim's take
The Sim made the Rams a slight favorite at a neutral site: 56% to beat the 49ers, with a projected score of 25-23 (LA by 2).
Final: 49ers 27, Rams 7. The Sim's pick was wrong.
49ers: last 5 games
Rams: last 5 games
Last meetings: 49ers vs. Rams
- 2025, Week 10 LA 42 at SF 26 Rams won
- 2025, Week 5 SF 26 at LA 23 (OT) 49ers won
- 2024, Week 15 LA 12 at SF 6 Rams won
- 2024, Week 3 SF 24 at LA 27 Rams won
- 2023, Week 18 LA 21 at SF 20 Rams won
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More Week 1 games
All Week 1 picks- Patriots vs. Seahawks recap
- Bears vs. Panthers recap
- Buccaneers vs. Bengals recap
- Saints vs. Lions recap
- Bills vs. Texans recap
- Ravens vs. Colts recap
- Browns vs. Jaguars recap
- Falcons vs. Steelers recap
- Jets vs. Titans recap
- Cardinals vs. Chargers recap
- Dolphins vs. Raiders recap
- Packers vs. Vikings recap
- Commanders vs. Eagles recap
- Cowboys vs. Giants recap
- Broncos vs. Chiefs recap
Schedule and scores: nflverse. Picks: the Sim, Hizzle's own model. Power rankings: Buck Kincaid. Times are Central. Not affiliated with the NFL.