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Bills vs. Panthers

NFL Week 8, 2025 season. Sunday, Oct 26, 2025, 12:00 PM CT. Bank of America Stadium. Referee: Craig Wrolstad.

Bills
4-2 going in
Final
40-9
Panthers
4-3 going in

The Sim's pick: Buffalo Bills

Sim right
74% Bills Panthers 26%
Projected score
BUF 27, CAR 20
Sim line
BUF -7
Backtest
made after kickoff

Beat the Sim: your pick

Picks for this game locked at kickoff. See the standings.

The Sim's take

The Sim made the Bills a clear favorite on the road: 74% to beat the Panthers, with a projected score of 27-20 (BUF by 7).

The Bills came in 4-2. The Panthers came in 4-3.

Final: Bills 40, Panthers 9. The Sim's pick was right.

Bills: last 5 games

Panthers: last 5 games

Last meetings: Bills vs. Panthers

  • 2021, Week 15 CAR 14 at BUF 31 Bills won
  • 2017, Week 2 BUF 3 at CAR 9 Panthers won
  • 2013, Week 2 CAR 23 at BUF 24 Bills won
  • 2009, Week 7 BUF 20 at CAR 9 Bills won
  • 2005, Week 12 CAR 13 at BUF 9 Panthers won

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Schedule and scores: nflverse. Picks: the Sim, Hizzle's own model. Power rankings: Buck Kincaid. Times are Central. Not affiliated with the NFL.