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Hizzle

Colts vs. Rams

NFL Week 4, 2025 season. Sunday, Sep 28, 2025, 3:05 PM CT. SoFi Stadium. Referee: Carl Cheffers.

Colts
3-0 going in
Final
20-27
Rams
2-1 going in

The Sim's pick: Los Angeles Rams

Sim right
28% Colts Rams 72%
Projected score
IND 20, LA 27
Sim line
LA -6.5
Backtest
made after kickoff

Beat the Sim: your pick

Picks for this game locked at kickoff. See the standings.

The Sim's take

The Sim made the Rams a clear favorite at home: 72% to beat the Colts, with a projected score of 27-20 (LA by 6.5).

The Colts came in 3-0. The Rams came in 2-1.

Final: Colts 20, Rams 27. The Sim's pick was right.

Colts: last 5 games

Rams: last 5 games

  • L 26-33 at Eagles Week 3
  • W 33-19 at Titans Week 2
  • W 14-9 vs Texans Week 1
  • L 22-28 at Eagles Divisional Round, 2024
  • W 27-9 vs Vikings Wild Card Round, 2024

Last meetings: Colts vs. Rams

  • 2023, Week 4 LA 29 at IND 23 (OT) Rams won
  • 2021, Week 2 LA 27 at IND 24 Rams won
  • 2017, Week 1 IND 9 at LA 46 Rams won
  • 2013, Week 10 LA 38 at IND 8 Rams won
  • 2009, Week 7 IND 42 at LA 6 Colts won

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Schedule and scores: nflverse. Picks: the Sim, Hizzle's own model. Power rankings: Buck Kincaid. Times are Central. Not affiliated with the NFL.